HAN-P-21
Sang Jeon Chung
Sungkyunkwan University
Professor and Dean
South Korea
Antibody, ADC, DNA-Encoded Peptide Library
Academic Career
B.S., 1990, Sungkyunkwan University; Ph.D., 1996 POSTECH (advisor: Dong H. Kim); Postdoctoral training, 1997-1998, SCRIPPS (advisor: Chi-Huey Wong) and 2000-2003, Harvard University (advisor: Gregory Verdine); Principal Scientist, 2003-2013, KRIBB, Associated and full Professor, 2013-2017, Dongguk University Dept Chemistry; 2017-present, Professor (Tenured), Sungkyunkwan University School of Pharmacy
Selected Publications
Improved safety of chimeric antigen receptor T cells indirectly targeting antigens via switchable adapters. Park, HB, et al. Nat. Comm. 15 (1), 1-17 (2024).
Prodigious catalytic activity towards reduction of 4-hydroxynitrobenzene sodium salt using one-pot synthesized ZnO-Pd nanobolts. Tripathi, R., et al. Surf. Interfaces 44, 103580 (2024)
Network pharmacology and molecular docking approaches to elucidate the potential compounds and targets of Saeng-Ji-Hwang-Ko for treatment of type 2 diabetes mellitus. Ko, M. et al. Comp. Biol. Med. 149, 106041 (2022)
Site-selective antibody–drug conjugation by a proximity-driven S to N acyl transfer reaction on a therapeutic antibody. Lee, T., et al. J. Med. Chem. 65, 7, 5751–5759 (2022).
Photoconjugation of an Fc-Specific Peptide Enables Efficient DAR 2 Antibody–Drug Conjugate Formation. Lee, T., et al. Org. Lett. 22 (21), 8419-8423 (2020)
Monitoring metal–amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening, Lee, H. et al. Chem. Sci., 10, 1000–1007 (2019)
Ginkgetin, a biflavone from Ginkgo biloba leaves, prevents adipogenesis through STAT5-mediated PPARγ and C/EBPα regulation, Cho, Y., et al. Pharmacol. Res. 139, 325–336 (2019)
Homogeneous detection of caspase-3 using intrinsic fluorescence resonance energy transfer (iFRET), Kang, H., et al. Biosens. Bioelectron. 67, 413-418 (2015)
Why My Lab?
Join Our Chemical Biology Lab!
Located in the School of Pharmacy, our lab integrates organic chemistry and biochemistry to drive drug discovery. We develop ADCs with potent natural product payloads and innovate DNA-encoded peptide libraries for immunology and GPCR drug research. Our biochemistry team specializes in novel antibody discovery and ADC/peptide activity studies using in vitro, in cell, and in vivo assays. Starting Fall 2025, we offer a fully funded, all-English International Graduate Program for Pharmaceutical Science. Gain expertise and contribute to groundbreaking research!
