HAN-P-29
Billy Wai-Lung Ng
The Chinese University of Hong Kong
Assistant Professor
China
Chemical Glycobiology, Chemical Proximity, Medicinal Chemistry, Ferroptosis, Drug Discovery
Academic Career
Principal Investigator, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong (CUHK), 2019 - Present; Postdoctoral Training, Harvard Medical School, 2016 - 2019; Postdoctoral Training, University of Oxford, 2014 - 2016; Fulbright Scholar, MIT, 2013 - 2014; B.Sc. & Ph.D. in Chemistry, CUHK, 2007 -2014
Selected Publications
Lactone-to-lactam editing alters the pharmacology of bilobalide. JACS Au 4, 3537–3546 (2024)
Targeted protein O-GlcNAcylation using bifunctional small molecules. J. Am. Chem. Soc. 146, 9779–9789 (2024).
Design and Synthesis of Bicyclo[4.3.0]nonene Nucleoside Analogues. Org Lett 25, 9002–9007 (2023).
Simeprevir suppresses SARS- CoV-2 replication and synergizes with remdesivir. ACS Cent Sci 7, 792–802 (2021).
Coronavirus RNA proofreading: molecular basis and therapeutic targeting. Mol. Cell 79, 710–727 (2020).
Phase separation in viral infections. Trends Microbiol 30, 1217–1231 (2022).
Palladium-catalyzed arylation of carbasugars enables the discovery of potent and selective SGLT2 inhibitors. Angew Chem Int Ed 55, 13818–13821 (2016).
Why My Lab?
Located in a top medical school, our young chemical biology lab (~5 years) is passionate about mentoring international students and fostering global collaborations. We specialize in organic synthesis and molecular biology, with a strong focus on translating discoveries into clinical applications through close collaborations with clinicians.
Let’s connect: billyng@cuhk.edu.hk
