HAN-P-31
Bengang Xing
Nanyang Technological University
Professor
Singapore
Chemical Biology, Molecular Probe & Imaging, Bio-Labeling, Nano-Theranostics
Academic Career
B.S., 1994, Xinjiang Normal University; Ph.D., 2000, Nanjin University (advisor: Prof. TANG Wenxia); Postdoctoral Training, 2000-2003, The Hong Kong University of Science and Technology (advisor: Prof. XU Bing); 2003-2004 Crump Institute of Molecular Imaging, UCLA (advisor: Prof. RAO Jianghong), 2004-2006 (Molecular Imaging Program at Stanford, Stanford University (advisor: Prof. RAO Jianghong); Assistant Professor, 2006-2011, Associate Professor (Tenured), 2011-2019, Professor, 2019-present, Nanyang Technological University, Singapore
Selected Publications
“A Nitroreductase-activatable Metabolic Reporter for Covalent Labeling of Pathological Hypoxia in Tumorigenesis,” Z. Wang*, J. Lau, Z. Ren, Z. Gong, X. Liu, B. G. Xing*, Angew. Chem. Intl. Ed, 2024, 64, e202411636.
“Enzymes in Synergy: Bacteria Specific Molecular Probe for Locoregional Imaging of Urinary Tract Infection in vivo”, Y. H., et al., B. G. Xing*, Angew. Chem. Intl. Ed, 2024, 64, e202406843. "VIP" paper.
“Hypoxia Deactivates Epigenetic Feedbacks via Enzyme-derived Clicking Proteolysis Targeting Chimeras”; D. C. Thang, et al., B. G. Xing* Sci. Adv. 2022, 8 (50), abq2216, Highlighted in "BioArtMED", "ixsdh."
“Cyanine-Dyad Molecular Probe for Simultaneous Profiling of Multiple Radical Species Evolution in Bacterial Infection". Z. Wang, et al., B. G. Xing*, Angew. Chem. Intl. Ed, 2021, 60, 16900, Highlight as “VIP” paper,""Angew Chem. "Wechat Platform", "X-Mol".
“Multispectral Optoaccoustic Imaging of Dynamic Redox Correlation and Pathophysiological Progression Utilizing Upconversion Nanoprobes.” X. Z. Ai, et al., B. G. Xing*. Nature Commun, 2019, 10, 1087. Featured by “X-Mol” and “Nature Commun. Editor’s Highlights".
“Remote Regulation of Membrane Channel Activity by Site-specific Localization of lanthanide-doped Upconversion Nanocrystals.” X. Ai, et al,. B. G. Xing*. Angew. Chem. Intl. Ed, 2017, 56, 3031, Featured in "BackCover", and Highlighted in “Advanced Science News, Wiley”, and “X-MoL”.
"In vivo Covalent Cross-linking of Photon-converted Rare-earth Nanostructures for Tumor Localization and Theranostics". X. Z. Ai, et al., B. Xing, Nature Commun. 2016, 7, 10432. Featured in “BioDiscover”, “ScienceNet” and “X-MoL”.
“Real-Time Visualization of Cell-Surface Proteolytic Enzyme Functions Using a Small-Molecule FRET Probe” J. Mu, et al., B. G. Xing, Angew Chem. Intl. Ed., 2014, 53, 14357-14362.
Why My Lab?
Our research group has been fully conducting the interdisciplinary research at the interfaces of chemical biology, molecular probe and imaging, biolabeling, and Nano-theranostics in CCEB, NTU. Our group also fosters a collaborative and academically stimulating environment with a focus on nurturing team members’ scientific growth.
